ELISA FICARRA

Associate Professor

Photo
Phone +39 0110907180 / 7180 (DAUIN)
Email elisa.ficarra@polito.it
Scientific branch ING-INF/05 - SISTEMI DI ELABORAZIONE DELLE INFORMAZIONI
(Area 0009 - Ingegneria industriale e dell'informazione)
Publications PORTO - Publications Open Repository TOrino
Curriculum
[ Carrier] Master Degree in Electrical Engineering, specialization in Biomedical Engineering at the University of Bologna, Italy, March 2001. International Ph.D. of excellence in Systems and Computer Science at the Politecnico di Torino, Italy. Jan. 2003 Dec. 2005. Assistant Professor at the Politecnico di Torino, DAUIN, since 2008. [Project Management Experiences and Professional Activity] Visiting scientist at the Computer Science Dep. of Stanford University (California, USA) for a project on DNA-protein interaction and docking analysis, 2002. Visiting scientist at the Integrated System Laboratory EPFL, Lausanne, Switzerland, for a research project on Bioimaging and functional genomics, Jan. Dec. 2005. Collaboration with the Dep. of Computer Science at the Stanford University, CA USA, and the Integrated Systems Centre at the EPFL of Lausanne, Switzerland for a project of Bioimaging and Gene expression correlation with clinical and immunohistochemical data, Oct 2005 Sept. 2006. Local Coordinator of CIPE project Clinical-molecular correlation in the lung cancer with alteration of the epidermal growth factor, 2005 2008. Local technical coordinator of ENIAC European funded project "CSI - Central Nervous System Imaging", 2010 - 2013. Scientific supervisor of MS, graduated and Ph.D. students, and of Post-doc Fellows at the Politecnico di Torino concerning projects on Bioimaging and Bioinformatics. Reviewer for several international journals including Nature Nanotechnology Associate Editor of the journal IEEE Transactions on Information Technology and Biomedicine. Teacher of Informatics, Clinical Image processing, Bioinformatics for master degrees and Ph.D program courses. [Research interests and Competence] Biomedical image processing and Molecular imaging High-throughput omic data mining and heterogeneous data integration (e.g. classification and clustering techniques, machine learning, data integration, molecular networks design) Next Generation Sequencing analysis (e.g. RNA-Seq, alignment, alternative splicing, transplicing and translocations analysis, WES) miRNA regulation prediction [Scientific Contributions] Development of AFM high resolution image processing techniques for DNA analysis Development of automated techniques for high resolution confocal images of pathological tissue. Development of automated techniques for the correlation of protein activity in carcinoma tissues and tissue gene expressions. Development of automated techniques for the prediction of miRNA gene targets the modeling of corresponding biological pathways. Development of bio-text mining approaches and service oriented infrastructures for the correlation between biomolecular and biomedical data in scientific publications exploiting heterogeneous sources of information. Development of algorithms for ASL-fMRI image reconstruction. Development of algorithms for MRI/PET system attenuation correction. Development of an algorithm for the detection of translocations in RNA-Seq data (NGS technologies). Development of a pipeline for the analysis of mutations and translocations in RNA-Seq and WES data Development of grid/cloud infrastructures for NGS data analysis. [Collaborations] RNA-Seq and WES: Center for Functional Genomics (Verona, Italy) Medical School at the University of Torino (Italy) (CeRMS, Torino, Italy) Research Center on Experimental Medicine Institute for Cancer Research and Treatment (Torino, Italy), Medical School at the University of Bologna. (Italy) Center for Computational Biology & Bioinformatics at the Columbia University (NY, USA) Istituto Superiore Mario Boella, Torino (Italy) miRNA regulative pathways analysis: Helsinki University (FL) Multiscale modaling: Southampton University (UK) Imaging: Medical School at the University of Verona (Italy) Philips Healthcare (NL) University College London (UK)
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